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The science behind Proto-col

With over 17 years of research and expertise in collagen supplementation, we designed our skin and body supplements with specific Bioactive Collagen Peptides®, each with a unique molecular size to target specific areas in the body:

  • Collagen Beauty Supplements to improve skin, hair, nails, and cellulite.
  • Collagen Supplements for Joints - targeting cartilage tissue.
  • Our latest innovation Complete Collagen offers twice the science to benefit both skin and connective tissues, which keep your body flexible and mobile.

How do Proto-col's collagen supplements work?

The true digestibility of the Bioactive Collagen Peptides® is 98.4%. Their unique single helix structure (a narrower shape than other collagen peptides) is absorbed almost intact by the gut cells. Their strong peptide bond is resistant to digestive enzymes that break down weaker peptide bonds. As a result, you consume more collagen and trigger your body to produce its own collagen.

The delivery format does not impact the bioavailability of our collagen supplements. Whether you prefer our collagen capsules, collagen tablets, or liquid collagen, they will work the same way.

The Bioactive Collagen Peptides® used in our supplements have been independently tested and consistently delivered strong results.

The clinical results

Clinical studies: improved skin, hair, nails and cellulite

Improved skin, hair, nails and cellulite

Skin results

SKIN

When orally consumed Bioactive Collagen Peptides® (VERISOL B®) systematically effects the collagen metabolism in the dermis by stimulating the collagen producing cells (fibroblasts).

Study 1 – Increased skin elasticity

Increased skin elasticity more pronounced results for women over 50

increase in skin elasticity after 4 weeks of supplementation with 2500mg or 5000mg of VERISOL B®. More pronounced results for women aged over 50.

Based on a double-blind study involving 69 women aged 35-55 taking a daily dose of 2500mg of VERISOL B® or 5000mg of VERISOL B® or a placebo for 4 weeks

Study 2 – Reduced wrinkle volume

After 8 weeks of supplementation with 2500mg of VERISOL:

Increase in procollagen I production

increase in pro collagen I

Increase in elastin

increase in elastin

Reduced wrinkle volume

decrease in wrinkle volume

Based on a double-blind study involving 108 women aged 45-65 taking a daily dose of 2500mg of VERISOL B® or a placebo for 8 weeks.

Reduced wrinkle volume before and after
Hair results

HAIR

Study 3 – Increase in hair thickness

31% increase in hair follicle cell proliferation rate

30% increase in hair follicle cell proliferation rate

In vitro tests on human follicle cells: After a 4-hour incubation period with VERSIOL®, the proliferation rate was on average 31% higher than in the untreated cells

Changes in hair thickness after 16 weeks with VERISOL® vs. Placebo

Changes in hair thickness after 16 weeks with VERISOL® vs. Placebo

Based on a double-blind study involving 44 healthy women aged 39-75, taking a daily dose of 2500mg of VERISOL® or a placebo for 16 weeks.

Nail results

NAILS

Study 4 – Improved growth and quality of nails

After 24 weeks:

The growth and quality of nails improved

Perceived their nails as longer

Perceived their nails as longer

Said their nails grew faster

Said their nails grew faster

Based on an open, single-centre clinical trial involving 25 women aged 18-50 with common symptoms of brittle nails, taking a daily dose of 2500mg of VERISOL B® for 6 months.

CELLULITE

Study 5 – Improvement of appearance of cellulite

11% reduction in skin waviness after 6 months of supplementation with 2500mg of VERISOL:

Increase skin elasticity and firmness

Reduce wrinkles and fine lines

Improve nail growth speed and resistance

Improve hair thickness

Choose a beauty supplement for skin, hair, nails and cellulite:

pure collagen capsules
collagen skin plus
collagen shot
complete collagen
collagen cordial

Clinical studies: healthy joints

HEALTHY JOINTS

Collagen is a protein that makes up around 30% of our total body protein, which is crucial for mobile joints, healthy bones and strong muscles, ligaments and tendons.

Through its vital role in connective tissues, collagen acts as a glue that helps hold us together.

The specific Bioactive Collagen Peptide® used in Proto-col’s joint supplements (FORTIGEL®) has been clinically tested and approved for its effects on relieving joint pain and regenerating healthy cartilage.

Study 1 – Improvement of the cartilage tissue

Change in the joint cartilage after 3 months (tissue sections*)

Progression without collagen

Progression with collagen

*Oesser S et al. (2007) Osteoarthritis Cartilage 15: C6 1-C62, 94

Study 2 – New generated cartilage tissue

Based on a double-blind randomised study involving 60 men and
women taking a daily dose of 10,000mg of FORTIGEL® or a placebo for 48 weeks.

Choose a supplement for healthy joints.

osteo plus
collagen body and joint

Clinical studies: a flexible and mobile body

FLEXIBILITY AND

STRENGTH

Ligaments bind bones together and tendons bind muscle to bone. Made of collagen, they are essential for movement control, stability, and better mobility.

TENDOFORTE®, the Bioactive Collagen Peptide® targets the collagen producing cells in tendons and ligaments and is designed to increase the health and quality of these crucial connecting elements of the body.

Study 1 – Improved mobility

Within 3 months, 60% of patients with chronic Achilles Tendinopathy returned to running faster.

Based on a double-blind placebo-controlled independent study involving 20 men and women with Achilles Tendinopathy aged 36 – 52 taking 2500mg of TENDOFORTE® for 12 weeks with a specialised exercise programme.

Our latest collagen innovation, Complete Collagen contains VERISOL® (skin, hair and nails) and TENDOFORTE® (tendons and ligaments) for vibrant skin and an active body.

Find out more

Clinical studies: improved skin, hair, nails and cellulite

Improved skin, hair, nails and cellulite

Skin results

SKIN

When orally consumed Bioactive Collagen Peptides® (VERISOL B®) systematically effects the collagen metabolism in the dermis by stimulating the collagen producing cells (fibroblasts).

Study 1 – Increased skin elasticity

Increased skin elasticity more pronounced results for women over 50

increase in skin elasticity after 4 weeks of supplementation with 2500mg or 5000mg of VERISOL B®. More pronounced results for women aged over 50.

Based on a double-blind study involving 69 women aged 35-55 taking a daily dose of 2500mg of VERISOL B® or 5000mg of VERISOL B® or a placebo for 4 weeks

Study 2 – Reduced wrinkle volume

After 8 weeks of supplementation with 2500mg of VERISOL:

Increase in procollagen I production

increase in pro collagen I

Increase in elastin

increase in elastin

Reduced wrinkle volume

decrease in wrinkle volume

Based on a double-blind study involving 108 women aged 45-65 taking a daily dose of 2500mg of VERISOL B® or a placebo for 8 weeks.

Reduced wrinkle volume before and after
Hair results

HAIR

Study 3 – Increase in hair thickness

31% increase in hair follicle cell proliferation rate

30% increase in hair follicle cell proliferation rate

In vitro tests on human follicle cells: After a 4-hour incubation period with VERSIOL®, the proliferation rate was on average 31% higher than in the untreated cells

Changes in hair thickness after 16 weeks with VERISOL® vs. Placebo

Changes in hair thickness after 16 weeks with VERISOL® vs. Placebo

Based on a double-blind study involving 44 healthy women aged 39-75, taking a daily dose of 2500mg of VERISOL® or a placebo for 16 weeks.

Nail results

NAILS

Study 4 – Improved growth and quality of nails

After 24 weeks:

The growth and quality of nails improved

Perceived their nails as longer

Perceived their nails as longer

Said their nails grew faster

Said their nails grew faster

Based on an open, single-centre clinical trial involving 25 women aged 18-50 with common symptoms of brittle nails, taking a daily dose of 2500mg of VERISOL B® for 6 months.

CELLULITE

Study 5 – Improvement of appearance of cellulite

11% reduction in skin waviness after 6 months of supplementation with 2500mg of VERISOL:

Choose a beauty supplement for skin, hair, nails and cellulite:

pure collagen capsules
collagen skin plus
collagen shot
collagen cordial
complete collagen

Clinical studies: healthy joints

HEALTHY JOINTS

Collagen is a protein that makes up around 30% of our total body protein, which is crucial for mobile joints, healthy bones and strong muscles, ligaments and tendons.

Through its vital role in connective tissues, collagen acts as a glue that helps hold us together.

The specific Bioactive Collagen Peptide® used in Proto-col’s joint supplements (FORTIGEL®) has been clinically tested and approved for its effects on relieving joint pain and regenerating healthy cartilage.

Study 1 – Improvement of the cartilage tissue

Change in the joint cartilage after 3 months (tissue sections*)

Progression without collagen

Progression with collagen

*Oesser S et al. (2007) Osteoarthritis Cartilage 15: C6 1-C62, 94

Study 2 – New generated cartilage tissue

Based on a double-blind randomised study involving 60 men and
women taking a daily dose of 10,000mg of FORTIGEL® or a placebo for 48 weeks.

Choose a supplement for healthy joints.:

osteo plus
collagen body and joint

Clinical studies: a flexible and mobile body

FLEXIBILITY AND

STRENGTH

Ligaments bind bones together and tendons bind muscle to bone. Made of collagen, they are essential for movement control, stability, and better mobility.

TENDOFORTE®, the Bioactive Collagen Peptide® targets the collagen producing cells in tendons and ligaments and is designed to increase the health and quality of these crucial connecting elements of the body.

Study 1 – Improved mobility

Within 3 months, 60% of patients with chronic Achilles Tendinopathy returned to running faster.

Based on a double-blind placebo-controlled independent study involving 20 men and women with Achilles Tendinopathy aged 36 – 52 taking 2500mg of TENDOFORTE® for 12 weeks with a specialised exercise programme.

Our latest collagen innovation, Complete Collagen contains VERISOL® (skin, hair and nails) and TENDOFORTE® (tendons and ligaments) for vibrant skin and an active body.

Find out more